(CANINE)
Dogs
Health topics
- Blue-green algae poses deadly risk to pets during summer heat Even brief contact with toxic algae can be deadly for pets in summer, warns a WSU expert, urging caution around all stagnant water.
- Shaping the future of veterinary medicine WSU researchers are using precision medicine to uncover hidden genetic mutations in pets, helping veterinarians predict, diagnose, and prevent deadly conditions before they strike.
- MDR1 Litter testing If I test one puppy in a litter for the MDR1 genotype do I need to test other puppies? If I know the MDR1 genotype of the parents, do I need to test the puppies?
- Genetic test can detect deadly bleeding disorder in dogs A new genetic test can identify dogs at risk of a potentially deadly disorder resulting in excessive bleeding and bruising in the hours and days following surgical procedures.
- Canine influenza Learn more about canine influenza, including subtypes H3N8 and H3N2, symptoms of the virus, prevention of spread, and diagnosis.
- MDR1 test pricing Why choose WSU for MDR1 testing Cats and dogs with a mutation in what is known as the MDR1 (multidrug resistance 1) gene can have severe adverse reactions to many common medications, including those frequently used to treat and prevent parasites like heartworms. Fortunately, Washington State University offers accurate genetic testing to determine if your […]
- MDR1 testing What you need to know about MDR1 testing Some dogs – including as many as 75% of specific herding breeds – and around 4% of all cats have a dangerous mutation in what is known as the MDR1 (multidrug resistance 1) gene, which, if undetected, can lead to severe adverse reactions to many common medications. […]
- Discoveries, innovations by WSU veterinarian saves countless animals During her more than two decades at Washington State University, Regents Professor Dr. Katrina Mealey has become a pioneer in veterinary pharmacogenetics and made countless contributions to veterinary medicine, most notably the discovery of a mutation in the MDR1 gene in dogs and cats that can lead to deadly reactions to common medications. The discoveries […]
- Problem medications for dogs Learn what medications may be dangerous for your dog with the MDRI genetic mutation. Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. Once WSU has determined your dog’s […]
- Is your pet at risk of an adverse reaction to common drugs? What is multidrug sensitivity? Some dogs and cats have a mutation in the MDR1 (multidrug resistance 1) gene also known as the ABCB1 gene, which plays an important role in limiting drug distribution to the brain and in enhancing the excretion of many drugs. Animals with the mutation may have severe adverse reactions – including […]
- Are heartworm prevention products safe if my dog has the MDR1 mutation? All heartworm products labeled for dogs in the United States have been tested in dogs with the MDR1 mutation as required by the FDA and have been found to be safe. Drugs such as ivermectin, selamectin, milbemycin, and moxidectin, are commonly used to treat and prevent parasites like heartworms. At low doses, such as those […]
- Dog breeds commonly affected by MDR1 mutation Dogs with a mutation in the MDR1 (multidrug resistance 1) gene may have severe and life-threatening reactions to some common drugs. Research has shown the mutation occurs more frequently in certain breeds. Approximately three of every four collies in the United States have the mutant MDR1 gene. The frequency is about the same in France […]
- Can you predict if a litter of puppies will have the MDR1 genetic mutation? If you know whether the sire and dam have the mutant MDR1 gene, you can accurately predict if puppies in their litter will have the MDR1 genetic mutation. The chart below details breeding pair combinations and outcomes: